Company Profile

Vertex Pharmaceuticals

Company Overview

At Vertex, we bring together the brightest minds in the relentless pursuit of creating transformative medicines for people with serious and life-threatening diseases. Founded in 1989 in Cambridge, Massachusetts, we are one of only a handful of biotechnology companies founded since 1976 that has discovered and developed four or more approved medicines in our own labs. In addition to the four medicines we’ve developed to treat the underlying cause of cystic fibrosis, we have ongoing research programs focused on the underlying mechanisms of other serious diseases.

Our U.S. headquarters are in Boston’s Innovation District, our International headquarters are located in London, UK, and we have research and development (R&D) sites and commercial offices in the U.S., Europe, Canada, Australia and Latin America. With more than two-thirds of our employees dedicated to research and development (R&D), we are consistently recognized as one of the industry’s top places to work, including nine consecutive years on Science magazine’s Top Employers list. For company updates and to learn more about us visit www.vrtx.com. You can also get to know us on Facebook, Twitter and YouTube.

Positions Available
  • 3 days ago

    Pharmacology Research Scientist

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:We are seeking a talented, self-motivated and collaborative in-vivo pharmacologist to join the integrated pharmacology team supporting late-stage drug discovery. The ideal candidate will have a strong foundation in pharmacology, work with a high degree of independence and be adept at conceptually designing, executing and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas. Key Duties and Responsibilities:Designs ...

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  • 5 days ago

    Medicinal Chemistry Research Scientist

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionVertex Pharmaceuticals has an exciting opportunity for a Research Scientist in the field of medicinal chemistry. Job responsibilities include the preparation of both single and focused sets of small organic molecules, developing and optimizing synthetic methods, creating and interpreting project-relevant Structure-Activity Relationship (SAR) and problem solving. Candidates must demonstrate an expert understanding of organic reaction mechanisms, formulation of executable synthetic ...

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  • 10 days ago

    Manufacturing Operations Support & Materials Management Manager (3rd Shift, 4/10)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionThe Manufacturing Operations Support & Materials Management Manager is the accountable off-shift superintendent for cGMP cleaning and materials management support for cell manufacturing sites located in Boston and Cambridge. This role provides general oversight for Materials Management and Manufacturing Support functions. The Manager will partner with with Manufacturing Operations, Quality Assurance, Facilities, and Vertex managed service partners for troubleshooting and resolving ...

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  • 21 days ago

    Senior Principal Research Scientist, Biomarkers Lead (Immunology)

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionGeneral Summary:The Biomarkers Senior Principal Research Scientist (Associate Director) is an independent leader with advanced scientific knowledge and expertise in biomarker development who develops and implements the clinical biomarker strategy for one or more programs and implements the biomarker plan during clinical development with no/minimal guidance. Experience in authoring and supporting regulatory filings and applicable areas of these filings is required. The incumbent ...

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  • 1 month ago

    Molecular and Cell Biology Principal Research Scientist, Targeted Drug Delivery

    Vertex Pharmaceuticals - San Diego, California, United States

    Job DescriptionVertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases - cystic fibrosis, pain, sickle cell disease and transfusion-dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of ...

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  • 1 month ago

    Vertex Spring 2026 Co-op, Engineering

    Vertex Pharmaceuticals - Boston, Massachusetts, United States

    Job DescriptionKickstart Your Career at Vertex!Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, ...

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